The Automated Glycohemoglobin Analyzer is a high-throughput benchtop system for quantitative HbA1c measurement in clinical laboratories. It uses ion-exchange HPLC with three elution buffers to deliver precise results in both NGSP and IFCC units within 1 minute per test. The instrument supports whole blood and diluted blood, features automatic sampling, hemolyzing, and mixing, and includes an RFID reagent management system for streamlined workflow.
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1. Fast
First test takes 2 minutes
1 Min/Test (60 tests/Hour)
Rotated sample rack loader
2. Precise
Ion exchange chromatography/Three elution buffers
Report in both NGSP and IFCC results
| Sample No.: 033 Sample ID: AI01-02 Position: sample type: hemolyzed blood Name: Gender: Age: Test Time: 2020-08-03 09:42:23 |
| Items | Results | Unit |
| HbA1c | 10.78 | % |
| HbA1c | 94.34 | mmol/mol |
| HbF | 1.10 | % |
| HbA1 | 12.28 | % |
| Name | % | Time | Area |
| FP | 0.09 | 0.17 | 0.87 |
| A1A | 0.66 | 0.23 | 6.34 |
| A1B | 0.8 | 0.29 | 8.05 |
| F | 1.10 | 0.37 | 10.57 |
| LA1C+ | 1.57 | 0.48 | 15.02 |
| SA1C | 10.78 | 0.59 | 87.82 |
| A0 | 86.65 | 0.79 | 892.90 |
3. Stable
Correlativity
AH-600 Measured value
Top Brand Analyzer
Measured Value(%)
Repeatability
Intra-batch assays (n=10)
| Low | High | |
| Mean | 5.1% | 10.1% |
| SD | 0.05 | 0.05 |
| CV | 0.94% | 0.51% |
Inter-batch assays (n=20)
| Low | High | |
| Mean | 5.1% | 10.2% |
| SD | 0.04 | 0.06 |
| CV | 0.87% | 0.56% |
4. Easy
One key operation, smart settings
Automatically sampling, hemolyzing and mixing
Applying in whole blood and diluted blood
Mixing loading for primary tubes and micro-cup
RFID scanner, management for reagent lot No., expiry date, and residue check
LIS bi-directional transmission with reports in both diagram and text
Hemoglobin A1c
Diagnostic Criteria of Type 2 Diabetes
| Standards of Diagnosis | Plasma Glucose & HbA1c |
| Classic symptoms of high blood sugar+ HbA1c | ≥6.5 % |
| or + FPG (Fasting Plasma Glucose) | ≥126 mg/dl |
| or + OGTT (Oral Glucose Tolerance Test) | ≥200 mg/dl |
|
If without classic symptoms, each test usually needs to be repeated on a second day to diagnose diabetes. |
|
Testing should be carried out in a health care setting (such as clinics or hospital lab)
Clinical Usage of HbA1c
1. Early screening and diagnosis of diabetes
2. Effect evaluation of glycemic control for treatment adjustment
3. Differential diagnosis between stress hyperglycemia and diabetes
4. Prevention, monitoring and evaluation for complications of diabetes
Regular HbA1c Measurement:
1. Once per 6 months for the diabetics with glycemia well controlled;
2. Once per 3 months for the diabetics with failed glycemia controlled or treatment adjustment needed.
Parameters:
| Model | AH-600 |
| Measurement Principle | Ion-exchange HPLC |
| Test Mode | Standard mode/Variant mode |
| Throughput | Standard mode: 60s/test
Variant mode: 96s/test |
| Items | Standard mode: FP, A1A, A1B, F, LA1C+, SA1C, A0
Variant mode: With additional HbS, HbC, HbD, HbE |
| Measurement Range | HbA1c: 3%~20% |
| Repeatability | CV≤1.0% |
| Sample Type | Whole blood and diluted blood |
| Sample Management | LIS loading, barcode scanning |
| Sample Loading Capacity | 10 samples/rack*9 racks. Continuous circulating rack sampling system |
| STAT | STAT priority |
| HbA1c Report Form | In both graphic and value repot with IFCC(mmol/mol) and NGSP(%) results |
| Consumable | Elution buffer, hemolysis & wash solution, column, filter, calibrator, control |
| Reagent Management | RFID scanning, automatically loading info of lot, expiry date and remains, etc. |
| Operation Interface | English operation software, HDMI touch screen |
| User Management | Authorization set for different levels |
| Data Storage | 100,000 results. Available for statistics, online queries, data backup, data export |
| Export &Communication | RS-232 (Bi-directional). Built-in thermal printer |
| Maintenance | Automatic maintenance in startup and off, alarm and error indication, daily maintenance reminder &guidance |
| Power Supply | AC100~240V, 50/60Hz |
| Product Size(W*D*H) | 560*590*490mm |
| Net Weight | 45kg |
| Packing Size(W*D*H) | 600*1100*600mm |
| Gross Weight | 58kg |
Reagent
| Reagent | Qty | Specification |
| Eluent 1 | 1 Bottle | 800ml/Bottle, room temperature |
| Eluent 2 | 1 Bottle | 800ml/Bottle, room temperature |
| Eluent 3/4 | 1 Bottle | 800ml/Bottle, room temperature |
| Hemolysis &Wash Solution | 1 Bottle | 2000ml/Bottle, room temperature |
| Chromatography Column | 1 Piece | 1 Column/Kit, 4~15℃ |
| Filter | 1 Piece | 600 Tests/Change, room temperature |
| Calibrator | 1 Kit | 1 Vial*Level 1+1 Vial*Level 2
4mL/vial, 2~8℃ |
| Quality Control | 1 Kit | 1 Vial*Level 1+1 Vial * Level 2
0.5mL/vial, 2~8℃ |
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